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Dr. William (Bill) Rowe, Sunday, 8-31-14 September 1, 2014

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Dr. William (Bill) Rowe, Sunday, 8-31-14

http://archived.thespaceshow.com/shows/2307-BWB-2014-08-31.mp3

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Guest:  Dr. William (Bill) Rowe.  Topics:  Cardiovascular & other issues for long duration human spaceflight.  Please direct all comments and questions regarding Space Show programs/guest(s) to the Space Show blog, http://thespaceshow.wordpress.com.  Comments and questions should be relevant to the specific Space Show program. Written Transcripts of Space Show programs are a violation of our copyright and are not permitted without prior written consent, even if for your own use. We do not permit the commercial use of Space Show programs or any part thereof, nor do we permit editing, YouTube clips, or clips placed on other private channels & websites. Space Show programs can be quoted, but the quote must be cited or referenced using the proper citation format. Contact The Space Show for further information. In addition, please remember that your Amazon purchases can help support The Space Show/OGLF. See http://www.onegiantleapfoundation.org/amazon.htm.   For those listening to archives using live365.com and rating the programs, please email me as to why you assign a specific rating to the show. This will help me bring better programming to the audience.

We welcomed Dr. Bill Rowe back to the program to discuss cardiovascular issues for human spaceflight & EVAs, plus many other issues pertaining to long duration spaceflight.  Note that we experienced serious phone line issues with Bill about 12 minutes into the program forcing us to stop for repairs.  Evidently the fiber phone lines now serving Dr. Rowe cause broadcast equipment problems.  Bill was able to go to a neighbor’s house to do the show but you will hear some line issues plus unusual cuts as I spliced together part of his opening to the point we were able to resume with a good phone line.  Once past that point, there were no further phone line issues.  During the first segment of our 2 hour 11 minute program, Dr. Rowe introduced us to his discussion main points and we began using his website for references throughout the show.  It is important to be on his website and go where he points at various times in the discussion (see http://www.femsinspace.com).  While parts of the discussion relied on medical terms and descriptions, our guest did an excellent job of breaking it down for us non-medical types to easily understand the information he was sharing with us.  Among the issues we talked about were cardiac issues that don’t present symptoms, plus the problems with increased adrenalin secretion in the body which happens in space.  Dr. Rowe spent significant time discussing the adrenalin issues citing known astronaut examples.  In fact when talking about the adrenalin levels in space, he said that within five days of being in space the levels are twice that of being on Earth.  Another issue brought up was possible cardiovascular damage for excessive exercise and here he cited the research projects he had been involved in with marathon running athletes.  He strongly suggested the use of regularly taken electrocardiograms on the crews while in space.  Next, Dr. Rowe talked about EVA issues, specifically cooling.  He explained other risks and made the case for future robotic EVA missions instead of human mission.  Before the segment ended, he had much to say about exercise in space.

In our second segment, Bill reviewed for us his comments on oxidative stress and suggested we follow along with his website submarine model, http://www.femsinspace.com/Oxidative_stress.htm.  A listener then emailed in that the ISS did have an ultrasound on board which could be used for the purposes Dr. Rowe suggested (see http://www.nasa.gov/mission_pages/station/research/benefits/ultrasound.html).  Bill talked more about lunar dust toxicity plus magnesium and calcium usage in space and in general.  He referenced former astronaut Jim Irwin losing consciousness for a brief time on the Moon & he provided the reference for that fact.  Rodent research on the ISS was discussed, then he got a listener question about possible different health standards for government trained and fit astronauts as compared to space tourists and possible private sector astronauts.  Near the end of our discussion, space tourism came up and he pointed out risks for the middle age, overweight segment of the space tourism market.  Bill spoke to pharmaceutical use in space and the issues with it.  Just before ending our discussion, he pointed out that for Mars he thought an all female crew was best given the advantages they have over men.  He did explain his comment.

If you have comments/questions, post them on TSS blog above.  You can reach Dr. Rowe through his website or me.

Dr. Marcelo Vazquez, Monday, 7-1-13 July 2, 2013

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Dr. Marcelo Vazquez, Monday, 7-1-13

http://archived.thespaceshow.com/shows/2040-BWB-2013-07-01.mp3

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Guest:  Dr. Marcelo Vazquez.  Topics:  Space radiation with a focus on humans to Mars.  Please direct all comments and questions regarding Space Show programs/guest(s) to the Space Show blog, http://thespaceshow.wordpress.com.  Comments and questions should be relevant to the specific Space Show program. Written Transcripts of Space Show programs are a violation of our copyright and are not permitted without prior written consent, even if for your own use. We do not permit the commercial use of Space Show programs or any part thereof, nor do we permit editing, YouTube clips, or clips placed on other private channels & websites. Space Show programs can be quoted, but the quote must be cited or referenced using the proper citation format. Contact The Space Show for further information. In addition, please remember that your Amazon purchases can help support The Space Show/OGLF. See www.onegiantleapfoundation.org/amazon.htm.   For those of you interested in the opportunity to submit feedback on the NRC congressionally mandated Human Spaceflight Study, please go to www.nationalacademies.org/humanspaceflight.  Please remember that your Amazon Purchases Can Help Support The Space Show/OGLF (http://www.onegiantleapfoundation.org/amazon.htm).

We welcomed back Dr. Marcelo Vazquez back to discuss space radiation and mostly human spaceflight to Mars though we covered much ground dealing with space radiation, the risk to humans, mitigation and shielding, as well as policy issues.  During the first segment of our 1 hour 38 minute program, we jumped right into it by my asking our guest about the radiation risks, exposure levels, and survival odds for both the Inspiration Mars mission and the Mars One effort to send settler to Mars on a one way mission starting late 2020 or 2021.  This was a detailed and comprehensive discussion of the issues for these missions, the state of the art shielding availability, possible technology advancements, and more.  We also talked about radiation & pregnancy on a Mars mission, radiation & a young child on Mars or in space, cosmic rays, solar events & extrapolations from radiation oncology.  Doug called to ask about the need for a solar storm shelter in case of a solar particle event. Before the end of the first segment, we talked about ISS analogs, antioxidants, and electromagnetic shielding possibilities.

In the second segment, Michael sent an article about the LRO analysis suggesting light weight materials and plastics might shield astronauts on the Moon.  Dr. Vazquez said this was in keeping with what was known.  Joel sent a note asking about RLIP76 and spaceflight, a subject on which our guest had much to say. Our guest went into detail about the radiation impact on a human system, including the destruction of blood vessels.  In this light, I asked him about radiation and epithelial cells & if this was a show stopper for HSF, especially to Mars.  Another question came in on antioxidants and while they might be helpful to some degree, they might also need to be taken at levels that are at or near toxic to humans.  Another listener asked about radiation & telomeres, then we talked about valid analog space radiation studies here on Earth.  I asked our guest about other nations doing HSF radiation research, then Jeff called in to discuss the Curiosity radiation findings and the regulatory questions involved since a person going to Mars would exceed the radiation dose allowed by existing OSHA & other regulations.  We talked about the validity of Inspiration Mars as a research study & as the program ended, we talked about neurological and cognitive radiation impact & some tests Inspiration Mars crews could do in this area on the mission.

Post your comments/questions on The Space Show blog above.  You can send a note to our guest by using my email address.

Dr. William (Bill) Rowe, Sunday, 6-2-13 June 2, 2013

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Dr. William (Bill) Rowe, Sunday, 6-2-13

http://archived.thespaceshow.com/shows/2021-BWB-2013-06-02.mp3

Guest:  Dr. William (Bill) Rowe.  Topics:  Moon walking astronauts, stress tests, cardiac problems,  HSF to Mars.  Please direct all comments & questions regarding Space Show programs/guest(s) to the Space Show blog, http://thespaceshow.wordpress.com.  Comments & questions should be relevant to the specific Space Show program. Written Transcripts of Space Show programs are a violation of our copyright & are not permitted without prior written consent, even if for your own use. We do not permit the commercial use of Space Show programs or any part thereof, nor do we permit editing, YouTube clips, or clips placed on other private channels & websites. Space Show programs can be quoted, but the quote must be cited or referenced using the proper citation format. Contact The Space Show for further information.

We welcomed back Dr. Bill Rowe to the program to discuss his important discovery regarding four Moon Walking astronauts.  In our first segment of this two hour discussion, Bill explained his latest research findings& what his conclusions mean for human spaceflight.  To find out more about Dr. Rowe’s research, to read his papers, & to learn more about telomeres, oxidative stress, & astronaut cardiac issues, visit his website www.femsinspace.com.  In this segment, Bill talked about damaging the lining of the endothelium, too much or too little adrenalin & magnesium, & the four Moon Walking astronaut abnormal stress tests.  Our discussion then turned to the Inspiration Mars flyby mission which our guest said was not survivable.  Bill went over his reasons for his conclusion regarding this proposed 501 day mission& talked about 1G being the law & what that means for our bodies to be in less than a 1G environment.  Bill then talked about telomeres & possible damage for the round trip Mars mission, plus he talked about the lack of an effective space exercise protocol as well as problems with prescription medications in space, including the need to deliver medicines subcutaneously but there is no such subcutaneous drug delivery system.  Several times during our discussion, Bill said we might not be ready for humans to Mars for a long time, he kept asking what the rush was to go so quickly.  He commented on the Buzz Aldrin cycler plan which he thought was doable 22 plus years from now assuming our research advanced in the time leading up to such a mission.  Bill talked about radiation, including the recent data NASA released from the RAD instrument on MSL in space & on the Martian surface.  Eric sent in a clarification comment about the possible death of an Inspiration Mars crew member& he asked Bill about his exercise statements which he said did not seem to be in agreement with statements made by other aerospace medicine professionals.  Dr. Dear emailed in a question from the UK about Bill’s thinking that there will be no survival chance re Inspiration Mars.  He compared that to the record in space held by the Soviet Cosmonaut on Mir, citing that record as reason to think that the crew could survive the 501 day Mars trip which would only be about 64 fewer days in space than the Mars flyby mission.

In our second segment, we talked about possible lessons learned from the Inspiration Mars flight & Dr. Rowe talked more about the Buzz Aldrin Mars plan.  Bill then moved to the issue of females being better suited for spaceflight than men.  He had much to say on this subject plus he has several papers addressing the subject on his website.  Hint: Iron toxicity is a big issue.  Dust issues were discussed in this segment& Bill talked again about his submarine analogy on oxidative stress from his website (www.femsinspace.com/Oxidative_stress.htm).  When asked for some recommendations, Bill talked about the need for centrifuge studies & suggested rat studies with an on orbit centrifuge.

Please post your comments/questions on The Space Show blog.  Dr. Rowe can be reached through his website or directly using RoweRun@aol.com.

Dr. William (Bill) Rowe, Sunday, 2-10-13 February 11, 2013

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Dr. William (Bill) Rowe, Sunday, 2-10-13

http://archived.thespaceshow.com/shows/1947-BWB-2013-02-10.mp3

Guest:  Dr. William (Bill) Rowe.  Topics:  Apollo astronauts cardiac & medical issues. Please direct all comments and questions regarding Space Show programs/guest(s) to the Space Show blog, http://thespaceshow.wordpress.com.  Comments and questions should be relevant to the specific Space Show program. Written Transcripts of Space Show programs are a violation of our copyright and are not permitted without prior written consent, even if for your own use. We do not permit the commercial use of Space Show programs or any part thereof, nor do we permit editing, YouTube clips, or clips placed on other private channels & websites. Space Show programs can be quoted, but the quote must be cited or referenced using the proper citation format. Contact The Space Show for further information.

     We welcomed Dr. Rowe back to the program to discuss his latest findings regarding four Apollo astronauts, lunar dust, microgravity, and cardiac conditions.  His work is presented on his website so do check it out, www.femsinspace.com.  Dr. Rowe’s latest findings came from his research using the Freedom of Information Act to get medical data from NASA after the recent passing of Neil Armstrong.  During our first segment, Bill explained what he found, what specific blood pressure and other information strongly suggests, and his comparison of the Armstrong data with that of several other Apollo astronauts per available data.  He also brought our attention to the problem independent researchers have in getting Apollo information and medical stats from NASA.  Bill used stress test blood pressure numbers and other medical information from the astronauts in question to illustrate his points and to back up his conclusions.  Most of our first segment was devoted to Dr. Rowe putting forth the information and his conclusions.  Bill took several email questions and listener calls, often wanting more information than he could provide because the reality is that there is an absence of additional information or relevant studies suggested.  One listener was asked if the ISS astronauts evidenced similar cardiac problems. Dr. Rowe was unable to answer that question due to the absence of information.

     In the second segment of this 2 hour 20 minute program, Dr. Rowe connected problems of lunar dust with urban pollution, suggesting microgravity studies that would benefit millions on Earth given how widespread the problem of urban pollution is on the planet.  One of the studies he proposed would use 30 female rats subjects to different calcium/magnesium rations on the ISS for six months.  Bill spent time in this segment explaining the importance of the calcium/magnesium ratio and what this means in space and for us back here on Earth, hence the rat study.  Dr. Rowe also talked about the difficulty of having a quality exercise RX for microgravity.  A listener asked about studies related to the Mt. St. Helens eruption several years ago re dust exposure.  Near the end of our discussion, Bill talked about their being no hurry to go to Mars, suggested many of the near term human spaceflight missions such as one way trips to Mars won’t happen for a long time because the human issues will not be resolved in the near term.  He also advocated the Moon first.  We talked about artificial gravity and I mentioned what other human factor gusts have said on air in that artificial gravity may not be the same as 1g here on Earth and may prove to not be a solution. Listeners did not like hearing that as they kept saying there would be an engineering solution to the microgravity issues.  Listener disagreements about artificial gravity not being the same as earth gravity continued long after the program ended.

    If you have comments/questions, please post them on The Space Show blog above.  You can contact Dr. Rowe through his website or through me.

Dr. William (Bill) Rowe, Sunday, 1-22-12 January 23, 2012

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Dr. William (Bill) Rowe, Sunday, 1-22-12

http://archived.thespaceshow.com/shows/1695-BWB-2012-01-22.mp3

Guest: Dr. William (Bill) Rowe.  Topics:  Space medicine issues, magnesium issues, microgravity, ISS experiments, and more.  You are invited to comment, ask questions, and discuss the Space Show program/guest(s) on the Space Show blog, http://thespaceshow.wordpress.com.  Comments, questions, and any discussion must be relevant and applicable to Space Show programming. Transcripts of Space Show programs are not permitted without prior written consent from The Space Show (even if for personal use) & are a violation of the Space Show copyright. We welcomed back to the show Dr. Bill Rowe for updates on his presentations in China and elsewhere, his continued research on the role of magnesium in space medicine, the role of telomeres and gender crew issues for long duration spaceflight including trips to Mars.  During the first segment of our two hour plus program, Dr. Rowe directed us to many of the pages, articles, and documents on his website, www.femsinspace.com.  I urge you to access the pages he directs us to at various times during his talk and follow along with him.  This is important.  In this segment, we talked about the latest telomere research and its application to space flight.  Bill proposed ISS rat experiments and what the experiments should tell us.  He also talked about the role of magnesium deficiency in cells in spaceflight.  He talked about the need to develop a subcutaneous replenishable silicon device/pump to deliver magnesium and explained why this was essential.  Dr. Rowe talked about cardio-vascular issues in spaceflight in the context of magnesium and the overall issues of vascular disease.  This took us into the area of gender lifespan differences and studies showing that an all female crew to Mars might be desirable.  Also in this segment, Dr. Rowe talked extensively about oxidative stress and referred us to his submarine diagram on his website, www.femsinspace.com/Oxidative_stress.htm.  Marshall called in to talk about the ISS and the need for artificial gravity, partial gravity, or 1 G.  Dr. Rowe said 1 G was essential for humans.  Dr. Paul Dear called in from the UK with several questions, including asking about the initiating events for the body to sense microgravity down at the cellular level.  Bill & Dr. Dear also talked about genomic selection for astronauts. 

In the second segment, Dr. Rowe continued his discussion of the first segment topics and his proposed rat experiment regarding telomeres. Many listener calls and emails came in and Dr. Rowe expanded the discussion to the role of calcium for space flight and the calcium/magnesium ratio or relationship.  He was asked why magnesium was not discussed by most human factors space medicine doctors. Dr. Jurist was also asked this question during his call, listen to what they said in response to this question.  Bill talked about exercise routines for spaceflight & said it was a challenge to know the right exercise RX.  Don’t miss his comments on this issue. Near the end, he used Columbus and sailing ships as an example saying we are not ready for long duration spaceflight or a trip to Mars.  Listen to how he and I explained this during the closing comments for the show as I helped Bill phrase his analogy. 

Post your comments/questions for Dr. Rowe on The Space Show blog URL above. Dr. Rowe can be reached via his website.

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